Trimethoxy flavone, pachypodol containing pogostemon cablin leaf extract shows broad spectrum antimicrobial activity

Autor:	Arthanareeswari Maruthapillai, Ganesh Munuswamy Ramanujam, S. Krithika, Muhammad Sadiq
Rok vydání:	2022
Předmět:	biology Traditional medicine fungi Ethyl acetate Antimicrobial medicine.disease biology.organism_classification Terpenoid Pogostemon Hexane chemistry.chemical_compound Phytochemical chemistry medicine Pachypodol Klebsiella pneumonia
Zdroj:	Materials Today: Proceedings. 50:297-300
ISSN:	2214-7853
DOI:	10.1016/j.matpr.2021.07.136
Popis:	Natural products have become a promising therapy for many pathogenic infectious conditions. In the present study, leaves of P. cablin were extracted using Hexane and ethyl acetate. Leaf Ethyl acetate extract showed significantly better antimicrobial activity against both Staphylococcus aureus 6538 (Gram-positive) (SA) and Klebsiella pneumonia ATCC 27,736 (Gram-negative) bacteria compared to the Hexane extract and was subjected to phytochemical analysis and chromatographic seperation. Phytochemical analysis of P. cablin leaf EtOAc extract showed the presence of Tannins, Flavanoids and Terpenoids. Subjecting the EtOAc leaf extract to column chromatographic separation resulted in the isolation of a trimethoxy flavone, pachypodol.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f775ef101841f213d068c549a89c02eb https://doi.org/10.1016/j.matpr.2021.07.136 Zobrazit plný text záznamu Full Text from ScienceDirect