Lipid Profile in Subclinical and Overt Hypothyroidism
| Autor: | A. Akila, V. Usha Padmini, C. Vignesh |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
endocrine system medicine.medical_specialty Pituitary Hypothyroidism endocrine system diseases medicine.diagnostic_test business.industry Fatty acid High density Lipid metabolism Metabolism Lipid degradation Endocrinology chemistry Internal medicine medicine lipids (amino acids peptides and proteins) Lipid profile business hormones hormone substitutes and hormone antagonists Subclinical infection |
| Zdroj: | IOSR Journal of Dental and Medical Sciences. 15:140-143 |
| ISSN: | 2279-0853 2279-0861 |
| DOI: | 10.9790/0853-150806140143 |
| Popis: | The effect of hypothyroidism on lipid metabolism is notable.Both synthesis and degradation of lipid are depressed, the latter especially so,the net effect being one of lipid accumulation.The decrease in lipid degradation may reflect a decrease in postheparin lipolytic activity as well as decrease delivery of lipid to degrading site.Although an increase in serum cholesterol is the most common abnormality of hypothyroidism,serum phospholipid and serum triglycerides are also increased and reverse happens with high density lipoprotein.Plasma free fatty acid is decreased and metabolism of free fatty acid is also impaired.These changes occur only in primary hypothyroidism,not in pituitary hypothyroidism. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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