Dialysate saving by automated control of flow rates: Comparison between individualized online hemodiafiltration and standard hemodialysis

Autor:	Lajos Major, Andreas Bock, Bernard Canaud, Klara Berta, Ralf Wojke, Enisa Mesic, Björn Wikström, Lajos Vaslaki
Rok vydání:	2011
Předmět:	medicine.medical_specialty business.industry medicine.medical_treatment Urology Hematology Treatment parameters Blood flow Online hemodiafiltration Automated control law.invention Surgery Hemodialysis Solutions Randomized controlled trial Nephrology law Medicine Hemodialysis business Dialysis
Zdroj:	Hemodialysis International. 15:522-529
ISSN:	1492-7535
DOI:	10.1111/j.1542-4758.2011.00577.x
Popis:	Cost reduction and quality improvement seem to be conflicting issues. However, online hemodiafiltration (oHDF) with new automatic functions offers a cost-efficient therapy compared to hemodialysis (HD). Seven dialysis centers conducted a randomized clinical trial with cross-over design: high-flux HD vs. postdilutional oHDF with functions coupling both dialysate and substitution flow rates to blood flow rates. During the 6 weeks of the study, all treatment parameters remained unchanged for HD and oHDF, apart from dialysate and substitution flow rate. Treatment data were recorded during each treatment, and predialytic and postdialytic concentrations of urea were recorded at the end of each study phase. The analysis involved 956 treatments of 54 patients. The mean dialysate consumption was 123.2 ± 6.4 l for HD and 113.4 ± 14.9 l for oHDF (p
Databáze:	OpenAIRE
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