ChemInform Abstract: A Concise Total Synthesis of (+)-Curacin A, a Novel Cyclopropyl-Substituted Thiazoline from the Cyanobacterium Lyngbya majuscula

Autor:	Gerald Pattenden, Tao Ye, James C. Muir
Rok vydání:	2010
Předmět:	chemistry.chemical_classification chemistry.chemical_compound chemistry biology Stereochemistry Thiazoline Total synthesis General Medicine Polyene biology.organism_classification Thioamide Lyngbya majuscula
Zdroj:	ChemInform. 29
ISSN:	1522-2667 0931-7597
DOI:	10.1002/chin.199830270
Popis:	A total synthesis of (+)-curacin A 1 which features a facile and selective thioacylation of the polyene amino-alcohol 2 with the benzotriazole-derived cyclopropyl thioamide 3, leading to 15, as a key step is described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f7505a7ad09f692b3a8aae08035331af https://doi.org/10.1002/chin.199830270 Zobrazit plný text záznamu Plný text