Comparing two different doses of propofol after sevoflurane induction for intubation in paediatric patients without use of neuromuscular blocking agents
| Autor: | Y R Chandrika, Khawer Muneer, K R Chandrakala, Hina Khurshid |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
business.industry
medicine.medical_treatment Hemodynamics General Medicine Neuromuscular Blocking Agents Sevoflurane Fentanyl 03 medical and health sciences 0302 clinical medicine 030202 anesthesiology 030225 pediatrics Anesthesia Medicine Intubation Airway management business Adverse effect Propofol medicine.drug |
| Zdroj: | Indian Journal of Clinical Anaesthesia. 7:389-393 |
| ISSN: | 2394-4994 2394-4781 |
| DOI: | 10.18231/j.ijca.2020.071 |
| Popis: | Introduction: In the practice of paediatric anaesthesia, intubation of trachea without using neuromuscular blocking agents is becoming commoner more so in conditions in which muscle relaxants are not preferred. Different combinations of drugs including opioids, intravenous agents and inhalational agents are being used for facilitating endotracheal intubation when muscle relaxants are not used. In this study we compared intubating conditions in paediatric patients after sevoflurane induction and propofol in two different doses. Materials and Methods: 80 children of 2 to 12 years age undergoing elective surgeries were divided into two groups P2 and P3 of 40 each. After sevoflurane induction and fentanyl 2mcg/kg I.V. group P2 received propofol 2mg/kg and group P3 received propofol 3mg/kg I.V. The two groups were compared with respect to intubating conditions and haemodynamic parameters. Results: Clinically acceptable intubating conditions were seen in all patients in both groups. Excellent intubating conditions were more in group P3 (87.5%) than group P2 (80%). Haemodynamic parameters showed no significant difference between the two groups. Conclusion: In paediatric patients, endotracheal intubation can be comfortably performed without muscle relaxants by using propofol and fentanyl with sevoflurane induction with no respiratory or haemodynamic adverse events. Propofol in a dose of 3mg/kg gives better intubating conditions than 2mg/kg without adverse haemodynamic effects, although 2mg/kg propofol also gives acceptable intubating conditions. Keywords: Paediatric patients, Intubating conditions, Propofol, Sevoflurane. |
| Databáze: | OpenAIRE |
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