ChemInform Abstract: Trimethylsilyl-1,3,4-oxadiazoles - New Useful Synthons for the Synthesis of Various 2,5-Disubstituted-1,3,4-oxadiazoles

Autor:	Andrej A. Tolmachev, Igor I. Pervak, Aleksandr A. Yurchenko, Evgenij V. Zarudnitskii, Anatolij S. Merkulov
Rok vydání:	2009
Předmět:	Substitution reaction Silanes Trimethylsilyl Synthon chemistry.chemical_element General Medicine Chloride chemistry.chemical_compound chemistry Electrophile Chlorine medicine Organic chemistry Reactivity (chemistry) medicine.drug
Zdroj:	ChemInform. 40
ISSN:	1522-2667 0931-7597
Popis:	The reactivity of 2-aryl-5-trimethylsilyl-1,3,4-oxadiazoles toward different types of electrophiles was investigated. These silanes readily react with chlorine, bromine, aliphatic acyl chlorides, 2-nitrobenzenesulfenyl chloride, and some reactive isocyanates affording the corresponding substituted 1,3,4-oxadiazoles. The reactions with carbonyl compounds proceed only in the presence of F − anions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f7199b3c817d903627652b0816b745e3 https://doi.org/10.1002/chin.200911142 Zobrazit plný text záznamu Plný text