Influence of sodium alginate and methylcellulose on hydrolysis and physicochemical properties of α-TCP based materials
| Autor: | D. Siek, Aneta Zima, Joanna Czechowska, Anna Ślósarczyk |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Cement
chemistry.chemical_classification Materials science Process Chemistry and Technology Simulated body fluid Diffusion 02 engineering and technology Polymer Biodegradation 010402 general chemistry 021001 nanoscience & nanotechnology Microstructure 01 natural sciences 0104 chemical sciences Surfaces Coatings and Films Electronic Optical and Magnetic Materials Hydrolysis Compressive strength Chemical engineering chemistry Materials Chemistry Ceramics and Composites 0210 nano-technology |
| Zdroj: | Ceramics International. 44:6533-6540 |
| ISSN: | 0272-8842 |
| DOI: | 10.1016/j.ceramint.2018.01.055 |
| Popis: | The effect of the sodium alginate and methylcellulose modifiers on hydrolysis, setting reaction, microstructure, mechanical and in vitro properties of α-TCP based materials was investigated. It was found that the presence of sodium alginate impeded α-TCP hydrolysis to hydroxyapatite, which may have a significant influence on resorbability, biodegradation and biological behavior of biomaterials. There were several reasons for these phenomena, such as: (I) the gelation of sodium alginate in the presence of Ca2+, (II) the creation of an organic layer which impedes the diffusion of water molecules to α-TCP and (III) the uptake of water molecules by sodium alginate. The inhibitory effect was not observed for methylcellulose and it was diminished in simulated body fluid. Additionally, it was demonstrated that the examined cements varied in their microstructure, setting times and compressive strengths, depending on the applied kind of a polymer additive. The cement containing sodium alginate had a higher compressive strength (20 ± 8 MPa) than the one with methylcellulose (17 ± 4 MPa) and the one lacking polymer (14 ± 4 MPa). All the developed materials exhibited high bioactivity in vitro. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect