| Autor: |
Ashay Karpe, Satish Rao, Deepika Nayek, Indu B Ambulkar, Pradip Kendre, Trinanjan Basu |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Journal of Global Oncology. 5:107-107 |
| ISSN: |
2378-9506 |
| Popis: |
107 Background: Geriatric head and neck squamous carcinomas (GHNC) treatment remains challenging due to multiple patient and treatment related factors. We analysed preliminary data for seventy HNC patients beyond 70 years of age treated by modulated radiotherapy (MRT). The objective was to realise the learning curve ahead. Methods: There were 70 patients (M:56,F:14) with median age of 78 years (70-96) treated by MRT at our centre. They were analysed for efficacy and acute side effects. Besides demographic and disease related parameters compliance to treatment, rate of hospitalisation, dependency of WHO ladder 3 analgesia and early clinico-radiological outcomes were analysed. Results: The median follow up was 12 months. 65% patients were locally advanced stage and 65% received radical MRT. For radical MRT the dose ranged between 66-70 Gy in 30-33 fractions and 5 patients received palliative MRT. 83% completed intended treatment with 30% had MRT interruptions. 48% patients required hospitalisation. 60% had comorbidities with 35% two or more types. 13 patients had concurrent chemotherapy and 48% had hospitalisation and 60% had feeding tubes.65% and 30% had post MRT endoscopic evaluation and imaging respectively. Among them 80% are loco-regionally controlled. 30% patients are long term (more than 3 months) tube dependent and morphine dependent. There were 5 deaths while on MRT both due to associated cardiac and pulmonary comorbidities. 40% and 65% of palliative and radical MRT patients respectively had complete response post MRT. All patients underwent psychological counselling and dietician evaluation. The median G8 screening score was 15. Conclusions: GHNC are a unique group with its own challenge. The learning curve was need of specialised setting and modern MRT for effective outcome. Non disease related concerns like alteration in daily quality of life, social engagement related issues, dementia and end of life care emerged as prominent issues beyond disease control. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
