Methylated uridylyl-(5? ? N)-phenylalanines

Autor:	Prokof'ev Ma, N N Preobrazhenskaya, Ledneva Rk, Zoe A. Shabarova, N. G. Shinskii
Rok vydání:	1969
Předmět:	Hydrolysis chemistry.chemical_compound chemistry Stereochemistry Radical Enzymatic hydrolysis Organic chemistry Uracil Reactivity (chemistry) General Chemistry Ring (chemistry) Phosphate Phosphoric acid
Zdroj:	Bulletin of the Academy of Sciences of the USSR Division of Chemical Science. 18:2157-2159
ISSN:	1573-9171 0568-5230
DOI:	10.1007/bf00906642
Popis:	1. Derivatives of uridylyl-(5′ → N)-phenylalanine were obtained, methylated on the ring nitrogen N3 and the phosphoric acid radical. 2. In studies of acid, alkaline, and enzyme hydrolysis of these compounds, it was established that CH3-groups in position 3 of uracil do not exert a significant influence on reactivity of the phosphoamide bond in uridylyl-(5′ → N)-phenylalanines. 3. Methylation of phosphate radicals stabilizes the phosphoamide bond and renders the 5-phosphoester bond more labile.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f6e30a8e849725cb6cdb36ef374bec38 https://doi.org/10.1007/bf00906642 Zobrazit plný text záznamu Full text from SpringerLink