The Role of Phagocytosis in the Production of Endogenous Pyrogen by Polymorphonuclear Leukocytes

Autor:	R. H. Mitchell, F. Goodale, G. W. Gander
Rok vydání:	1976
Předmět:	Gram-negative bacteria biology Chemistry Experimental model Phagocytosis chemical and pharmacologic phenomena hemic and immune systems Buffy coat Liver slice biology.organism_classification Latex particle Microbiology Pathogenesis Endogenous pyrogen
Zdroj:	Advances in Experimental Medicine and Biology ISBN: 9781468432992
DOI:	10.1007/978-1-4684-3297-8_22
Popis:	In 1948 Beeson (3) reported that granulocytes contain an endogenous pyrogen, which was later (4,5) shown to differ from the pyrogenic endotoxin of gram negative bacteria. Considerable work on the pathogenesis of fever by several investigators eventually yielded an experimental model for it (Fig. 1).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f6c166ec1c1fc43d49dd18d1843eaf97 https://doi.org/10.1007/978-1-4684-3297-8_22 Zobrazit plný text záznamu