‘Watch and wait’ after chemoradiotherapy for rectal cancer
| Autor: | David Wattchow, J. O. Keck, Tamara G. Mullaney, Amy L. Lightner, M. Johnston |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
business.industry Colorectal cancer General surgery General Medicine medicine.disease Optimal management 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Cohort Medicine 030211 gastroenterology & hepatology Surgery Observational study Patient group business Chemoradiotherapy Complete response Pelvic surgery |
| Zdroj: | ANZ Journal of Surgery. 88:836-841 |
| ISSN: | 1445-1433 |
| DOI: | 10.1111/ans.14352 |
| Popis: | Surgery remains the cornerstone of rectal cancer treatment. However, there is significant morbidity and mortality associated with pelvic surgery, and the past decade has illustrated that a cohort of rectal cancer patients sustain a remission of local disease with chemoradiation alone. Thus, questions remain regarding the optimal management for rectal cancer; namely, accurately identifying patients who have a complete pathologic response and determining the oncologic safety of the observational approach for this patient group. This review aims to summarize the current evidence to provide an overview to the 'watch and wait' approach in rectal cancer patients with a complete response to neoadjuvant chemoradiation therapy. |
| Databáze: | OpenAIRE |
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