Inhibition of Macrophage Superoxide Production by Two Prenylated Flavanones fromErythrina sigmoidea Hua
| Autor: | Nicole Cotelle, J.P. Hénichart, J-P Catteau, D. Pesando, J-L Bernier |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
chemistry.chemical_classification
Antioxidant NADPH oxidase biology Superoxide Stereochemistry medicine.medical_treatment Radical biology.organism_classification law.invention chemistry.chemical_compound Enzyme chemistry Prenylation law medicine biology.protein Molecular Medicine Electron paramagnetic resonance Erythrina |
| Zdroj: | Natural Product Letters. 3:79-86 |
| ISSN: | 1057-5634 |
| Popis: | Two prenylated flavanones namely sigmoidin A (SA) and sigmoidin B (SB) have been extracted from Erythrina sigmoidea Hua, a plant of Cameroon traditionally used in local medicine. An antioxidant activity was found and ascribed either to a direct reaction with O2 − or to a direct and/or indirect action on the membrane-bound enzyme NADPH oxidase. The formation of stable radicals was also demonstrated by electron spin resonance spectroscopy (ESR) and related to the antioxidant activity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|