Issues in the Reconstruction of Gene Order Evolution

Autor:	Robert Warren, Zhenyu Yang, Chunfang Zheng, Adriana Muñoz, David Sankoff, Zaky Adam, Vicky Choi, Qian Zhu
Rok vydání:	2010
Předmět:	Comparative genomics Computer science Chromosome Chromosomal rearrangement Bioinformatics Genome Computer Science Applications Theoretical Computer Science Order (biology) Computational Theory and Mathematics Hardware and Architecture Evolutionary biology Phylogenomics Gene Software
Zdroj:	Journal of Computer Science and Technology. 25:10-25
ISSN:	1860-4749 1000-9000
DOI:	10.1007/s11390-010-9301-9
Popis:	As genomes evolve over hundreds of millions years, the chromosomes become rearranged, with segments of some chromosomes inverted, while other chromosomes reciprocally exchange chunks from their ends. These rearrangements lead to the scrambling of the elements of one genome with respect to another descended from a common ancestor. Multidisciplinary work undertakes to mathematically model these processes and to develop statistical analyses and mathematical algorithms to understand the scrambling in the chromosomes of two or more related genomes. A major focus is the reconstruction of the gene order of the ancestral genomes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f694822cddd62b24b30a6c5ed2a3baf3 https://doi.org/10.1007/s11390-010-9301-9 Zobrazit plný text záznamu Full text from SpringerLink