High Exercise Capacity Attenuates the Risk of Early Mortality After a First Myocardial Infarction
| Autor: | Steven J. Keteyian, Clinton A. Brawner, Roger S. Blumenthal, Jonathan K. Ehrman, Gabriel E. Shaya, Rupert K. Hung, Mouaz H. Al-Mallah, Waqas Qureshi, Khurram Nasir, Michael J. Blaha |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
business.industry Retrospective cohort study 030229 sport sciences General Medicine Odds ratio 030204 cardiovascular system & hematology medicine.disease Lower risk Metabolic equivalent 03 medical and health sciences 0302 clinical medicine Internal medicine Cardiology Physical therapy Risk of mortality Medicine Myocardial infarction Myocardial infarction diagnosis business Cohort study |
| Zdroj: | Mayo Clinic Proceedings. 91:129-139 |
| ISSN: | 0025-6196 |
| DOI: | 10.1016/j.mayocp.2015.11.012 |
| Popis: | Objective To examine the effect of objectively measured exercise capacity (EC) on early mortality (EM) after a first myocardial infarction (MI). Patients and Methods This retrospective cohort study included 2061 patients without a history of MI (mean age, 62±12 years; 38% [n=790] women; 56% [n=1153] white) who underwent clinical treadmill stress testing in the Henry Ford Health System from January 1, 1991, through May 31, 2009, and suffered MI during follow-up (MI event proportion, 3.4%; mean time from the exercise test to MI, 6.1±4.3 years). Exercise capacity was categorized on the basis of peak metabolic equivalents (METs) achieved: less than 6, 6 to 9, 10 to 11, and 12 or more METs. Early mortality was defined as all-cause mortality within 28, 90, or 365 days of MI. Multivariable logistic regression models were used to assess the effect of EC on the risk of mortality at each time point post-MI adjusting for baseline demographic characteristics, cardiovascular risk factors, medication use, indication for stress testing, and year of MI. Results The 28-day EM rate was 10.6% overall, and 13.9%, 10.7%, 6.9%, and 6.0% in the less than 6, 6 to 9, 10 to 11, and 12 or more METs categories, respectively ( P P P =.006; 90 days: OR, 0.90; 95% CI, 0.86-0.95; P P Conclusion Higher baseline EC was independently associated with a lower risk of early death after a first MI. |
| Databáze: | OpenAIRE |
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