Structural elucidation and α‑glucosidase inhibitory activity of a new xanthone glycoside from Lomatogonium rotatum (L.) Fries es Nym
| Autor: | Ao-ri-ge-le Chen, Guo-jun Zhang, Nabuqi Bao, Su-ya Bai, Mei-li Wang, Qinghu Wang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
chemistry.chemical_classification
In vitro test Flavonoid glycosides Stereochemistry Organic Chemistry Positive control Glycoside Plant Science Biochemistry Analytical Chemistry chemistry.chemical_compound chemistry Lomatogonium rotatum Xanthone medicine α glucosidase inhibitory Acarbose medicine.drug |
| Zdroj: | Natural Product Research. 36:4311-4315 |
| ISSN: | 1478-6427 1478-6419 |
| DOI: | 10.1080/14786419.2021.1995864 |
| Popis: | A new xanthone glycoside, 1,8-dihydroxyl-2,5-dimethoxy-xanthone-6-O-β-D-glucoside (1), along with two known xanthone glycosides and two flavonoid glycosides were isolated from the aerial parts of Lomatogonium rotatum (L.) Fries es Nym. The structure of 1 was elucidated by analysis of its spectroscopic data, including UV, IR, HR-ESI-MS and extensive 1 D and 2 D NMR techniques. In vitro test, compound 1 behaved similarity to swertianolin against α‑glucosidase and more potent inhibitory effects than the positive control, acarbose. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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