Familial Risk for Common Diseases in Primary Care

Autor: Nan E. Rothrock, Mack T. Ruffin, Wendy S. Rubinstein, Jennifer L. Beaumont, Paula W. Yoon, Erin J. Starzyk, Suzanne M. O'Neill, Catharine Wang, James M. Galliher, Louise S. Acheson
Rok vydání: 2009
Předmět:
Zdroj: American Journal of Preventive Medicine. 36:506-514
ISSN: 0749-3797
0016-4658
DOI: 10.1016/j.amepre.2009.03.002
Popis: Context Family history is a risk factor for many common chronic diseases, yet it remains underutilized in primary care practice. Background Family Healthware™ is a self-administered, web-based tool that assesses familial risk for CHD; stroke; diabetes; and colorectal, breast, and ovarian cancer, and provides a personalized prevention plan based on familial risk. The Family Healthware Impact Trial evaluated the tool. Design In this cluster RCT, participants completed baseline and 6-month follow-up surveys. The intervention group used Family Healthware directly after the baseline survey. Controls used the tool after completing the follow-up survey. Setting/participants Patients aged 35–65 years with no known diagnosis of these six diseases were enrolled from 41 primary care practices. Main outcome measures The prevalence of family-history–based risk for coronary heart disease (CHD); stroke; diabetes; and colorectal, breast, and ovarian cancer was determined in a primary care population. Results From 2005 to 2007, 3786 participants enrolled. Data analysis was undertaken from September 2007 to March 2008. Participants had a mean age of 50.6 years and were primarily white (91%) women (70%). Of the 3585 participants who completed the risk assessment tool, 82% had a strong or moderate familial risk for at least one of the diseases: CHD (strong=33%, moderate=26%); stroke (strong=15%, moderate=34%); diabetes (strong=11%, moderate=26%); colorectal cancer (strong=3%, moderate=11%); breast cancer (strong=10%, moderate=12%); and ovarian cancer (strong=4%, moderate=6%). Women had a significantly ( p p ≤0.02) more likely to have a strong family history for CHD, stroke, and diabetes. Older participants were significantly ( p ≤0.02) more likely to report a strong family history for CHD and stroke as well as colorectal and breast cancer. Conclusions This self-administered, online tool delineated a substantial burden of family-history–based risk for these chronic diseases in an adult, primary care population. Trial registration NCT00164658.
Databáze: OpenAIRE
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