Popis: |
Atherosclerotic cardiovascular disease is the leading cause of mortality worldwide. Evidence suggests that the risk of atherosclerosis complications associated not only with local changes within atherosclerotic plaque (such as the state necrotic core or fibrous cap), but also with the state of blood or systemic factors. Circulating levels of cytokines, prothrombotic factors or acute phase reactants may play a role in the occurrence of acute stroke in the presence of affected vessels, even in the absence of stenosis. For example, increased serum biomarkers such as C-reactive protein, cytokines - predict the progression of atherosclerosis and risk of stroke. Stroke, may be caused by atherosclerosis of large arteries supplying the brain, or it may affect smaller branches inside the skull. |