Osseointegration Enhancement by Zr doping of Co-Cr-Mo Implants Fabricated by Electron Beam Melting
| Autor: | Felicia Suska, Anders Palmquist, Yuichiro Koizumi, Hiroaki Matsumoto, Patrik Stenlund, Shingo Kurosu, Akihiko Chiba |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Zirconium
Materials science Alloy Metallurgy Biomedical Engineering chemistry.chemical_element engineering.material equipment and supplies Bone tissue Industrial and Manufacturing Engineering Osseointegration Corrosion medicine.anatomical_structure chemistry engineering medicine General Materials Science Implant Composite material Material properties Engineering (miscellaneous) Titanium |
| Zdroj: | Additive Manufacturing. 6:6-15 |
| ISSN: | 2214-8604 |
| DOI: | 10.1016/j.addma.2015.02.002 |
| Popis: | Direct osseous healing to prosthetic components is a prerequisite for the clinical success of uncemented treatment in total hip replacements (THR). The demands imposed on the material properties are constantly being stepped up to withstand the impact of an active lifestyle and ensure lifelong integration. Cobalt–chromium–molybdenum (Co-Cr-Mo) materials are interesting for their excellent mechanical stability, corrosion resistance and possibility to be produced by additive manufacturing into complex designs with modifiable stiffness. The bone response to Co-Cr-Mo is regarded as inferior to that of titanium and are usually cemented in THR. The hypothesis in the present study was that a low amount of Zr in the Co-Cr-Mo alloy would improve the bone response and biomechanical anchorage. The results showed significantly higher implant stability for the Co-Cr-Mo alloy with an addition of 0.04% Zr after eight weeks of healing in rabbits, while no major differences were observed in the amount of bone formed around the implants. Further, bone tissue grew into surface irregularities and in direct contact with the implant surfaces. It is concluded that additively manufactured Co-Cr-Mo alloy implants osseointegrate and that the addition of a low amount of Zr to the bulk Co-Cr-Mo further improves the bone anchorage. |
| Databáze: | OpenAIRE |
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