The Clinical Aspects of Rift Valley Fever Virus in Household Pets.: III. Pathologic Changes in the Dog and Cat

Autor: John Q. Mitten, Jerry S. Walker, Norman S. Remmele, Frederick Klein, Edward L. Stephen, Richard Carter
Rok vydání: 1970
Předmět:
Zdroj: Journal of Infectious Diseases. 121:25-31
ISSN: 1537-6613
0022-1899
DOI: 10.1093/infdis/121.1.25
Popis: The pathologic changes that occur in natural and experimental Rift Valley fever (RVF) have been described for sheep, lambs, cattle, calves, and a variety of other species [1-4]. The primary lesion is in the liver and consists of focal necrosis, eosinophilic intranuclear granules, and hyaline eosinophilic cytoplasmic bodies very similar to the Councilman body in yellow fever. Experimental RVF as it occurs in the canine and feline species has now been characterized in the accompanying papers [5, 6]. This report describes the pathologic changes that develop in these 2 species in response to inoculation of the RVF virus. The pathology of the experimental disease in laboratory mice has been well documented [710]. The pathologic changes occurring in SwissWebster mice are also reported here as control material for the disease in the dogs and cats.
Databáze: OpenAIRE