Magnetite Nanoparticle Dispersions Stabilized with Triblock Copolymers
Autor: | Martin Saunders, J. S. Riffle, and T. G. St. Pierre, J. Jonathan Harburn, Jonathan D. Goff, A. Y. Carmichael, L. A. Harris |
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Rok vydání: | 2003 |
Předmět: |
chemistry.chemical_classification
Materials science General Chemical Engineering Nanoparticle chemistry.chemical_element General Chemistry Polymer Magnetic susceptibility chemistry.chemical_compound chemistry Chemical engineering Ferrimagnetism Polymer chemistry Materials Chemistry Copolymer Magnetic nanoparticles Cobalt Magnetite |
Zdroj: | Chemistry of Materials. 15:1367-1377 |
ISSN: | 1520-5002 0897-4756 |
Popis: | Magnetic nanoparticles that display high saturation magnetization and high magnetic susceptibility are of great interest for medical applications. Magnetite nanoparticles display strong ferrimagnetic behavior and are less sensitive to oxidation than magnetic transition metal nanoparticles such as cobalt, iron, and nickel. For in vivo applications, well-defined organic coatings are needed to surround the magnetite nanoparticles and prevent any aggregation. The goal of this research was to develop complexes of magnetite nanoparticles coated with well-defined hydrophilic polymers so that they could be dispersed in aqueous fluids. Focal points have included the following: (1) Investigations of polymer systems that bind irreversibly to magnetite at the physiological pH, (2) the design of block copolymers with anchor and tail blocks to enable dispersion in biological fluids, and (3) investigations of copolymer block lengths to maximize the concentration of bound magnetite. Hydrophilic triblock copolymers with ... |
Databáze: | OpenAIRE |
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