Magnetite Nanoparticle Dispersions Stabilized with Triblock Copolymers

Autor: Martin Saunders, J. S. Riffle, and T. G. St. Pierre, J. Jonathan Harburn, Jonathan D. Goff, A. Y. Carmichael, L. A. Harris
Rok vydání: 2003
Předmět:
Zdroj: Chemistry of Materials. 15:1367-1377
ISSN: 1520-5002
0897-4756
Popis: Magnetic nanoparticles that display high saturation magnetization and high magnetic susceptibility are of great interest for medical applications. Magnetite nanoparticles display strong ferrimagnetic behavior and are less sensitive to oxidation than magnetic transition metal nanoparticles such as cobalt, iron, and nickel. For in vivo applications, well-defined organic coatings are needed to surround the magnetite nanoparticles and prevent any aggregation. The goal of this research was to develop complexes of magnetite nanoparticles coated with well-defined hydrophilic polymers so that they could be dispersed in aqueous fluids. Focal points have included the following: (1) Investigations of polymer systems that bind irreversibly to magnetite at the physiological pH, (2) the design of block copolymers with anchor and tail blocks to enable dispersion in biological fluids, and (3) investigations of copolymer block lengths to maximize the concentration of bound magnetite. Hydrophilic triblock copolymers with ...
Databáze: OpenAIRE