HPLC of Peptides and Peptide Diastereoisomers on ODS-and Cyanopropyl-Silica Gel Column Packing Materials

Autor:	J. G. Lloyd-jones, K. Sugden, C. Hunter
Rok vydání:	1980
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Chromatography chemistry Silica gel Phase (matter) Diastereomer Molecular Medicine Peptide Methanol Acetonitrile High-performance liquid chromatography
Zdroj:	Journal of Liquid Chromatography. 3:1335-1352
ISSN:	0148-3919
DOI:	10.1080/01483918008062780
Popis:	The use of hplc for the separation of various peptide diastereoisomers without the need for sample pre-treatment is described. The effect of the concentration of acetonitrile in the mobile phase on the retention of peptides on ODS- and Cyanopropyl-bonded phases is discussed and compared with the effect of methanol. The use of temperature and pH to control the relative retention of peptides on cyano phase is also discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f62e5905a9f3e63b1370c23e05074741 https://doi.org/10.1080/01483918008062780 Zobrazit plný text záznamu