Expression and Purification of Membrane Proteins in Different Hosts

Autor:	Eshagh Bandani, Fatemeh Abarghooi Kahaki, Saeed Khalili, Zahra Payandeh, Sakineh Monzavi, Abolfazl Jahangiri, Hadi Bamehr
Rok vydání:	2020
Předmět:	010405 organic chemistry Chemistry Pharmacology toxicology Cell Bioengineering 01 natural sciences Biochemistry 0104 chemical sciences Analytical Chemistry Cell biology Folding (chemistry) medicine.anatomical_structure Membrane protein Drug Discovery medicine Molecular Medicine
Zdroj:	International Journal of Peptide Research and Therapeutics. 26:2077-2087
ISSN:	1573-3904 1573-3149
DOI:	10.1007/s10989-019-10009-2
Popis:	Membrane proteins play important functions, such as cellular communication and transferring materials in the cell. Many membrane proteins are involved in human diseases. However, little information is available on their structure, stability and folding. To study their structure, membrane proteins should primarily be produces in large amounts. However, production of these proteins is limited by various technical issues. Developing novel strategies to circumvent these issues seems to be highly important to proceed in membrane protein science. In this review, we have summarized the recent findings which can promote membrane protein expression and purification.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f61ecdfb92610b8b96775b99510592a3 https://doi.org/10.1007/s10989-019-10009-2 Zobrazit plný text záznamu Plný text ve formátu PDF