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Objectives: Conventional upper intestinal endoscopy is usually performed to diagnose Helicobacter pylori (H. pylori)-associated diseases, using gastric mucosa from the biopsy. The objective of the study was to identify the prevalence of H. pylori and its relation with endoscopic findings and histopathological features in dyspeptic adult patients. Methods: Gastroduodenal biopsy specimens were collected from 143 adult dyspeptic patients who attended the outpatient Department of Gastroenterology, Bangabandhu Sheikh Mujib Medical University (BSMMU) and Dhaka Medical College Hospital (DMCH), for endoscopy. H. pylori were identified by rapid urease test (RUT), ureC gene PCR, and histological staining (Giemsa). Results: The study population was categorized as H. pylori positive cases 47(32.9%) and H. pylori negative cases 96 (67.1%) based on the case definition used in the study. The highest rate of H. pylori infection was found in the age group between 41-50 years (25.5%). Endoscopically, 101 (97.1%) dyspeptic patients had gastritis, and the majority of H. pylori infections were found among histopathologically diagnosed duodenal ulcer patients. Endoscopic findings were significantly correlated with histological findings (p |
