P1657GRAFT- AND PATIENT-SURVIVAL IN TRANSPLANT KIDNEY PATIENTS UNDERGOING TRANSPLANT BIOPSIES

Autor:	Björn Peters, Salmir Nasic, Lars Mjörnstedt, Bernd Stegmayr, Marie Felldin, Johan Mölne
Rok vydání:	2020
Předmět:	Transplantation medicine.medical_specialty Nephrology business.industry medicine Transplant kidney Patient survival business Surgery
Zdroj:	Nephrology Dialysis Transplantation. 35
ISSN:	1460-2385 0931-0509
Popis:	Background and Aims Kidney transplantation is a frequent treatment in uremic patients. However, long term patency is limited. The aim of this study was to investigate the histological findings in transplant biopsies in relation to clinical outcome in patients. Method 1542 patients (36.4 % women) were included if they had a first kidney transplant registered in a quality assessment registry (period October 24, 1968 and August 28, 2017) and also had registered a first transplant kidney biopsy during the period January 1, 2007 until Mars 2, 2018. Graft- and patient-survival analysis was performed by Kaplan-Meier- and Cox-regression-analysis (adjusted for age and gender). Data are presented as Hazard Ratio (HR) and 95% Confidence Intervals (CI). A two-sided p-value of Results Patients with primary and recurrent glomerulonephritis (GN) found in the biopsy had a worse graft- (70% at 5-year) and patient-survival (85% at 5-year) compared to all other diagnoses (p Conclusion Patients with GN and patients with TGP had a worse outcome in both graft- and patient-survival. Awareness should focus on the patients who die soon after graft-loss.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f5fbf013e0e571e0335b5c1bd41a2f71 https://doi.org/10.1093/ndt/gfaa142.p1657 Zobrazit plný text záznamu