A New Method for the Synthesis of Substituted 8,9,10,11-Tetrahydroindolo[1,2-a]Quinoxalin-6(5H)-Ones

Autor: E. A. Khafizova, Il'dar Kh. Rizvanov, Dmitry B. Krivolapov, Vakhid A. Mamedov, Anastasiya I. Zamaletdinova, Oleg G. Sinyashin, Julia K. Voronina, Ekaterina V. Mironova, Saniya F. Kadyrova
Rok vydání: 2017
Předmět:
Zdroj: Chemistry of Heterocyclic Compounds. 53:560-567
ISSN: 1573-8353
0009-3122
Popis: The reaction of 1-(cyclohexen-1-yl)pyrrolidines with 3-(α-chlorobenzyl)quinoxalin-2(1H)-ones resulted in the formation of 8,9,10,11-tetrahydroindolo[1,2-a]quinoxalin-6(5H)-ones via a tandem sequence of Stork enamine alkylation and intramolecular annulation. Oxidative dehydrogenation gave indolo[1,2-a]quinoxalin-6(5H)-one.
Databáze: OpenAIRE