Identification of by-products in phenylisocyanate pre-column derivatization by thermospray liquid chromatography-mass spectrometry

Autor:	D. Baylocq-Ferrier, F. Pellerin, S. Rakotomanga, Arlette Baillet
Rok vydání:	1991
Předmět:	Chromatography Chemistry Elution Organic Chemistry Clinical Biochemistry Thermospray Mass spectrometry Biochemistry Analytical Chemistry chemistry.chemical_compound Liquid chromatography–mass spectrometry Pre column derivatization Methanol Derivatization Phenylisocyanate
Zdroj:	Chromatographia. 32:125-129
ISSN:	1612-1112 0009-5893
Popis:	Thermospray liquid chromatography-mass spectrometry has been applied to the identification of by-products in precolumn derivatization by phenylisocyanate. These byproducts are eluted early in the same chromatographic region as the low molecular weight derivatives and were located by chromatographic analysis of a blank sample. Their identification would offer further qualitative information in the use of phenylisocyanate as a derivatizing agent. Five compounds resulted from the reaction of phenylisocyanate and the reaction medium were identified: two from a reaction between phenylisocyanate and methanol, two from the reaction between phenylisocyanate and water, and one from the polymerisation of phenylisocyanate.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f5bc128801b748b7b51f0488366c2396 https://doi.org/10.1007/bf02325014 Zobrazit plný text záznamu Full text from SpringerLink