Role of the silymarin on the prolactin gene expression in the pituitary, estrogen and progesterone hormones of western rats during lactation
| Autor: | Doaa Hashim Jawad, Wefak Jbori Albazi, H. B Mahmood |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | International journal of health sciences. :6996-7004 |
| ISSN: | 2550-696X 2550-6978 |
| DOI: | 10.53730/ijhs.v6ns5.10219 |
| Popis: | Objective: To see how dose of Silymarin aqueous extracts affected prolactin hormone gene expression in pituitary glands and Androgen hormone in serum samples of female experimental rats throughout nursing. Methods: 24 adult healthy, Two sets of pregnant rats were created (12 each group) and treated as follows for ten days postnatal. G 1 were intubated orally distal water serving as control while, G 2 were intubated orally Silymarin (200 mg\kg\day). Results: The findings show that Silymarin had a strong influence on mRNA–PRL expression in pituitary glands, with a rise in Estrogen and a decline in Progesterone levels. Conclusion: The focus of this study mention a new evidence of the role of Silymarin on the prolactin gene expression for increasing the milk production and level of estrogen & progesterone hormones. |
| Databáze: | OpenAIRE |
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