Mortality among World Trade Center rescue and recovery workers, 2002-2011
| Autor: | William Holden, Moshe Shapiro, Roberto Lucchini, Benjamin J. Luft, Jacqueline Moline, Michael Crane, Cheryl R. Stein, Dana Hashim, Sylvan Wallenstein, Iris Udasin |
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| Rok vydání: | 2016 |
| Předmět: |
Gerontology
medicine.medical_specialty education.field_of_study business.industry Proportional hazards model Hazard ratio Population Public Health Environmental and Occupational Health 010501 environmental sciences 01 natural sciences National Death Index 3. Good health 03 medical and health sciences 0302 clinical medicine Standardized mortality ratio Epidemiology Medicine 030212 general & internal medicine business education 0105 earth and related environmental sciences Cause of death Cohort study Demography |
| Zdroj: | American Journal of Industrial Medicine. 59:87-95 |
| ISSN: | 0271-3586 |
| DOI: | 10.1002/ajim.22558 |
| Popis: | Background Rescue and recovery workers responding to the 2001 collapse of the World Trade Center (WTC) sustained exposures to toxic chemicals and have elevated rates of multiple morbidities. Methods Using data from the World Trade Center Health Program and the National Death Index for 2002–2011, we examined standardized mortality ratios (SMR) and proportional cancer mortality ratios (PCMR) with indirect standardization for age, sex, race, and calendar year to the U.S. general population, as well as associations between WTC-related environmental exposures and all-cause mortality. Results We identified 330 deaths among 28,918 responders (SMR 0.43, 95%CI 0.39–0.48). No cause-specific SMRs were meaningfully elevated. PCMRs were elevated for neoplasms of lymphatic and hematopoietic tissue (PCMR 1.76, 95%CI 1.06–2.75). Mortality hazard ratios showed no linear trend with exposure. Conclusions Consistent with a healthy worker effect, all-cause mortality among responders was not elevated. There was no clear association between intensity and duration of exposure and mortality. Surveillance is needed to monitor the proportionally higher cancer mortality attributed to lymphatic/hematopoietic neoplasms. Am. J. Ind. Med. 59:87–95, 2016. © 2016 Wiley Periodicals, Inc. |
| Databáze: | OpenAIRE |
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