Abstract P315: Depressive Symptoms and Cardiovascular Health Among Young Adults in Puerto Rico

Autor: Milagros C Rosal, Andrea Lopez-Cepero, Israel Almodovar, Catarina Kiefe, Katherine L Tucker, Sharina Person, Jose Rodriguez-Orengo, Cynthia Perez
Rok vydání: 2023
Předmět:
Zdroj: Circulation. 147
ISSN: 1524-4539
0009-7322
DOI: 10.1161/circ.147.suppl_1.p315
Popis: Background: Depressive symptoms are associated with cardiovascular disease (CVD) incidence, morbidity and mortality. Less is known about the association between depressive symptoms and overall cardiovascular health (CVH) of young adults, an age group that commonly experiences depressive symptoms. We examined the association between depressive symptoms and a metric of overall CVH among young Puerto Ricans, a high risk but understudied population. Measures: We used data from PR-OUTLOOK, a study of CVH among individuals aged 18-29 residing in Puerto Rico, obtained between September 2020 and September 2022. Depressive symptoms were assessed using the 10-item Center for Epidemiologic Studies Depression Scale (CES-D-10). CVH was assessed using the AHA Life’s Essential 8 metric, which includes modifiable behavioral (nicotine exposure, diet, physical activity, sleep health) and biological (body mass index- BMI, blood lipids, blood pressure, and blood glucose) components. For this analysis, this metric was modified to exclude diet. Higher scores (range 0-100), overall and for each component, indicate better CVH. Covariates included age, sex, marital status, and childhood material deprivation. Multivariable linear regression models were used to assess the relationships of CES-D-10 score with overall CVH score and its individual components. An interaction term for sex and CES-D-10 was added to the models to examine potential differences by sex. Results: The sample (n=964; mean age: 22.6 ±3.1) was largely female (64%) and single (89%), and a third (33%) reported having experienced material deprivation in childhood. Over half (58.6%) reported depressive symptoms above the cut-off for likely clinical depression (CES-D-10 >10). The overall mean CVH score was 80.2±12.8, with almost half of the sample (42.8%) having a score < 80. Mean scores for the CVH components were lowest for physical activity (57.2±43.2) and BMI (71.4±33.9). In adjusted models, significant inverse associations were observed between CES-D-10 with overall CVH (-4.21, 95%CI: -5.84,-2.58) and several CVH components: nicotine exposure (-4.28; 95%CI: -8.28,-0.28), physical activity (-9.32; 95%CI: -14.87,-3.78), BMI (-6.54; 95%CI: -10.94,-2.15), and blood pressure (-3.02; 95%CI: -5.81,-0.23). No significant interaction was observed between CES-D-10 and sex. Conclusion: Depressive symptoms were inversely associated with CVH and four of the seven assessed CVH components. Longitudinal analyses should elucidate the potential contribution of depressive symptoms to reduction in CVH in young adults. Understanding factors associated with CVH among young Puerto Ricans may help elucidate CVD prevention targets for this vulnerable population.
Databáze: OpenAIRE
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