Iodine-catalyzed sulfonylation of sulfonyl hydrazides with tert-amines: a green and efficient protocol for the synthesis of sulfonamides
| Autor: | Lan Mei, Kui Du, Xiao-Ran Han, Jinchuan Liu, Qiang Li, Jinyang Chen, Tuanwu Cao |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Sulfonyl
chemistry.chemical_classification General Chemical Engineering chemistry.chemical_element 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Iodine 01 natural sciences Combinatorial chemistry 0104 chemical sciences Catalysis Selective cleavage chemistry 0210 nano-technology |
| Zdroj: | RSC Advances. 9:31212-31216 |
| ISSN: | 2046-2069 |
| DOI: | 10.1039/c9ra07361b |
| Popis: | This study provides a direct, sustainable and eco-friendly method for the synthesis of various sulfonamides via the sulfonylation of sulfonyl hydrazides with tert-amines. The method utilizes sulfonyl hydrazides to oxidize and couple with tertiary amines through selective cleavage of C–N bonds. In this reaction, molecular iodine was used as the catalyst and t-butyl hydroperoxide was used as the oxidant. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|