New drug AIMPILA targeted to AFP receptor: Oral anticancer therapy and biodistribution in vivo
| Autor: | Janneta Tcherkassova, Sergei Tsurkan, Vera Gorbunova, Helen Treshalina, Elena Yu. Grigorieva |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Drug Cancer Research Biodistribution business.industry Mechanism (biology) media_common.quotation_subject digestive oral and skin physiology Tumor cells digestive system diseases 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Oncology In vivo Apoptosis 030220 oncology & carcinogenesis embryonic structures Cancer research Medicine Receptor business neoplasms media_common |
| Zdroj: | Journal of Clinical Oncology. 36:e24232-e24232 |
| ISSN: | 1527-7755 0732-183X |
| DOI: | 10.1200/jco.2018.36.15_suppl.e24232 |
| Popis: | e24232Background: Non-covalent AFP-complexes attract a great interest due to their targeting ability to selectively induce apoptosis in the tumor cells using AFP-receptor (AR) mediated mechanism of... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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