| Autor: |
Yaremenko, A.I., Khaskevich, H.H., Onokhova, T.L. |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| DOI: |
10.34660/inf.2019.3.44544 |
| Popis: |
The number of patients with osteonecrosis of the jaw is increasing. The proposed classification allows osteo-destructive organization of various pathological manifestations and development of operation protocols. Patients self-estimation for the internal picture of the disease complements the results of the treatment check. The relationship of the dynamics of pro- and anti-inflammatory cytokines and immunoglobulins of the oral fluid with the effectiveness of surgical treatment in patients with chronic destructive processes of the jaw has been studied. A decrease in IL-4 at high IL-8 levels after the completion of treatment indicates an imbalance of pro-and anti-inflammatory cytokines, and against the background of an increase in the level of immunoglobulins in the oral fluid, can be considered as a sign of the ineffectiveness of the treatment followed by a relapse of osteonecrosis. With successful treatment, there is a restoration of interdependence between pro- and antiinflammatory cytokines against the background of a decrease in initially higher levels of IgG and slgA in the oral fluid. In parallel, biochemical and immunological studies are objective prognostic tests. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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