PRURITUS OF PREGNANCY AND JAUNDICE INDUCED BY ORAL CONTRACEPTIVES
| Autor: | B. Blenkinsop, T. Ptak, A. Medline, A. Gryfe |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
medicine.medical_specialty
Pregnancy Obstetrics business.industry Previous pregnancy Obstetrics and Gynecology General Medicine Portal tracts Jaundice medicine.disease Gastroenterology Mestranol Cholestasis Internal medicine medicine medicine.symptom business Liver parenchyma Histological examination medicine.drug |
| Zdroj: | Obstetrical & Gynecological Survey. 32:81-82 |
| ISSN: | 0029-7828 |
| Popis: | A case study of a patient who developed jaundice while taking oral contraceptives (OCs) is presented. The 18-year-old patient developed pruritus and mild jaundice within 1 month after beginning OC use. After a pregnancy in which jaundice did not develop she again showed these symptoms after resuming OC treatment with Ortho-Novum 1 (norethindrone 2 mg .05 mg mestranol). Histological examination of the liver revealed a marked degree of centrolobular cholestasis though there were no inflammatory changes in the liver parenchyma or portal tracts. Women who experience OC-induced jaundice generally have had pruritus or idiopathic jaundice during a previous pregnancy. |
| Databáze: | OpenAIRE |
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