EFFICACY OF JAVANESE TURMERIC ETHANOL EXTRACT IN ERADICATING STREPTOCOCCUS SANGUINIS AND PORPHYROMONAS GINGIVALIS BIOFILM
| Autor: | Rezon Yanuar, Dewi Fatma Suniarti, Widurini Djohan |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Streptococcus sanguinis
chemistry.chemical_compound Ethanol biology Chemistry Biofilm Pharmaceutical Science macromolecular substances biochemical phenomena metabolism and nutrition biology.organism_classification Pharmacology Toxicology and Pharmaceutics (miscellaneous) Porphyromonas gingivalis Microbiology |
| Zdroj: | International Journal of Applied Pharmaceutics. :18-22 |
| ISSN: | 0975-7058 |
| Popis: | Objective: Javanese turmeric is an Indonesian native medicinal plant with antibacterial activities. This study aimed to analyze the efficacy of identifiedJavanese turmeric ethanol extract (IJTEE) in eradicating Streptococcus sanguinis and Porphyromonas gingivalis biofilms.Methods: Biofilm assay: Single and combination biofilms formed at different phases were exposed to IJTEE in 0.5–25% concentrations for 1 h. Thepercentage of eradication was tested using the microtetrazolium assay.Results: The efficacy of IJTEE in eradicating the biofilm was equal to that of chlorhexidine against the early phase of biofilm formation. IJTEE is moreeffective against S. sanguinis biofilm formation than against P. gingivalis biofilm formation.Conclusion: IJTEE can eradicate S. sanguinis and P. gingivalis biofilms. |
| Databáze: | OpenAIRE |
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