Development of Safe, Scalable Nitric Acid Oxidation Using a Catalytic Amount of NaNO2 for 3-Bromo-2,2-bis(bromomethyl)propanoic Acid: An Intermediate of S-013420

Autor: Hiroshi Osato, Sumio Shimizu, Mikio Kabaki
Rok vydání: 2011
Předmět:
Zdroj: Organic Process Research & Development. 15:581-584
ISSN: 1520-586X
1083-6160
DOI: 10.1021/op1003133
Popis: A safe, scalable process was developed for nitric acid oxidation of 3-bromo-2,2-bis(bromomethyl)propan-1-ol (2) to give 3-bromo-2,2-bis(bromomethyl)propanoic acid (3), an intermediate in the synthe...
Databáze: OpenAIRE