The first enantioselective synthesis of 4-acetyl-3( R) - and 3( S )-(hydroxymethyl)-3,4-dihydro-2 H -pyrido[3,2- b ]oxazine

Autor:	N. Henry, G. Guillaumet, M.D. Pujol
Rok vydání:	2004
Předmět:	chemistry.chemical_compound chemistry Stereochemistry Organic Chemistry Drug Discovery Enantioselective synthesis Hydroxymethyl Biochemistry
Zdroj:	Tetrahedron Letters. 45:1465-1468
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2003.12.030
Popis:	A novel short and enantioselective synthetic approach to pyridobenzoxazines is reported in which ( R )- and ( S )-3-(hydroxymethyl)-3,4-dihydro-2 H -pyrido[3,2- b ][1,4]oxazine were first synthesized from readily available chiral glycidyl derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f524b424a8aa26204647a549d3972b2e https://doi.org/10.1016/j.tetlet.2003.12.030 Zobrazit plný text záznamu Full Text from ScienceDirect