Sonosynthesis and characterization of a fluorescent Trojan Horse based on magnetic nanoparticles
| Autor: | Cristina Díaz-Oliva, Marina Pérez-Ramos, D. Reyman |
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| Rok vydání: | 2020 |
| Předmět: |
Ferrofluid
Materials science Nanochemistry 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences Fluorescence 0104 chemical sciences Absorbance chemistry.chemical_compound chemistry Magnetic nanoparticles 0210 nano-technology Ethylene glycol Iron oxide nanoparticles Magnetite Nuclear chemistry |
| Zdroj: | Journal of Nanostructure in Chemistry. 10:105-113 |
| ISSN: | 2193-8865 2008-9244 |
| DOI: | 10.1007/s40097-020-00333-1 |
| Popis: | In this work, the sonosynthesis of a fluorescent nanocarrier based on iron oxide nanoparticles (mainly magnetite) conjugated with cisplatin, ethylene glycol (EG) and folic acid (FA) is presented. A spectroscopic study on the formation of a complex Fe(II)–FA was performed with the aim of evaluating how the adsorption of FA onto the magnetite takes place. The magnetite ferrofluids were characterized by Raman microspectroscopy, Transmission electron microscopy (TEM), UV–Vis spectroscopy (absorbance and fluorescence), X-ray fluorescence (TXRF) and X-ray diffraction (XRD). The structural analysis shows that Pt is part of the crystal structure of the system together with magnetite. The study also demonstrates that the cisplatin–folate interaction results in a less stable ferrofluid than that obtained in the absence of Pt. However, unlike the latter, the former shows fluorescence. Magnetic and fluorescent Trojan Horse containing platinum |
| Databáze: | OpenAIRE |
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