The nucleic acids, phospholipids and phosphoproteins of the human leucocyte

Autor:	I. F. Seits, I. S. Luganova
Rok vydání:	1958
Předmět:	Acute leukemia Phosphorus chemistry.chemical_element RNA Myeloid leukemia General Medicine Biology medicine.disease General Biochemistry Genetics and Molecular Biology Leukemia chemistry.chemical_compound chemistry Biochemistry Nucleic acid medicine Anaerobic exercise DNA
Zdroj:	Bulletin of Experimental Biology and Medicine. 46:953-956
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00787332
Popis:	Leucocytes in a healthy man contain the following (measured in gamma of phosphorus per 1 g dry weight of the cells): ribonucleic acid-1191±51; desoxyribonucleic acid-4235±278; phospholipids-2760±135; phosphoproteins-96±14. Leucocytes from the blood of patients with chronic myeloid leukemia contain correspondingly with the above: 1950±179; 435±299; 257±230 and 111±30. The quantity of phosphorus in the same compounds of leucocytes in the patients with chronic lymphadenosis equals 4043±210; 12,940±595; 2943±318 and 143±24, respectively. In acute leukemia: RNA-3590±453; DNA-6750±440; phosphoproteins-167±45. Phosphorus exchange is most intense in phosphoproteins and the least so in DNA, while RNA and phospholipids occupy a middle position. The rapidity of phosphorus exchange in all of these compounds does not depend on the conditions of aeration. Resynthesis of adenosinetriphosphate and phosphorus exchange in nucleic acids, phospholipids, and of phosphoproteins in leucocytes is carried out in anaerobic conditions in the same way as in aerobic.
Databáze:	OpenAIRE
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