Clinical and morphological characteristics of infective endocarditis

Autor:	V. I. Mazurov, V. I. Ulanova, V. A. Zinzerling
Rok vydání:	2020
Předmět:	03 medical and health sciences Pathology medicine.medical_specialty 0302 clinical medicine business.industry Infective endocarditis medicine 030212 general & internal medicine General Medicine 030204 cardiovascular system & hematology medicine.disease business
Zdroj:	Clinical Medicine (Russian Journal). 98:115-121
ISSN:	2412-1339 0023-2149
DOI:	10.30629/0023-2149-2020-98-2-115-121
Popis:	The aim of the study was to identify the features of the clinical course and morphogenesis of infective endocarditis (IE) in HIVinfected injecting drug users with concomitant hepatitis C virus infection in comparison with the clinical and morphological picture of endocarditis in persons without drug dependence. It was found that the causative agent of IE in HIV-infected patients was staphylococcus aureus (71.8%), and in persons without drug dependence in the etiology of the disease the conditionally pathogenic flora prevailed. In HIV-infected drug-dependent patients, the tricuspid valve was affected (82.7%), and in persons without drug dependence — isolated aortic valve damage (40%) and combined mitral and aorticvalve lesions (36.4%). Purulent sepsis complications in drug-dependent patients with IE are less common than in patients without drug dependence due to immunosuppression, which is present in HIV-infected persons.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f5017580fbc3a78979d3b5f4a91eac6f https://doi.org/10.30629/0023-2149-2020-98-2-115-121 Zobrazit plný text záznamu