Metal-Free Difunctionalization of Pyridines: Selective Construction of N-CF2H and N-CHO Dihydropyridines

Autor:	Xiangyang Tang, Sen Zhou, Wentao Zhao, Minjie Guo, Kongying Zhu, Guangwei Wang, Ze-Ying Sun
Rok vydání:	2021
Předmět:	Nucleophilic addition Metal free 010405 organic chemistry Chemistry Organic Chemistry Reactivity (chemistry) Physical and Theoretical Chemistry 010402 general chemistry 01 natural sciences Biochemistry Medicinal chemistry 0104 chemical sciences
Zdroj:	Organic Letters. 23:2205-2211
ISSN:	1523-7052 1523-7060
Popis:	The reactivity of N-difluoromethylpyridinium salts is seldom explored because of their instability and low availability. Here we present a novel nucleophilic addition of N-difluoromethylpyridinium ...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f4f0889fe9771cdc12790119b31e0f62 https://doi.org/10.1021/acs.orglett.1c00352 Zobrazit plný text záznamu