Inoculation of Macaca fascicularis With Simian Immunodeficiency Virus, SIV mne Immunologic, Serologic, and Pathologic Changes

Autor:	William R. Morton, Edward A. Clark, Thouless Me, LaRene Kuller, Che-Chung Tsai, Michael G. Katze, Raoul E. Benveniste, M.J. Gale, Shiu Lok Hu
Rok vydání:	1990
Předmět:	General Veterinary biology animal diseases Macaca nemestrina virus diseases Simian immunodeficiency virus medicine.disease_cause biology.organism_classification Virology Macaque Virus Serology biology.animal Lentivirus medicine Animal Science and Zoology Primate Viral disease
Zdroj:	Journal of Medical Primatology. 19:367-380
ISSN:	1600-0684 0047-2565
DOI:	10.1111/j.1600-0684.1990.tb00442.x
Popis:	Previous studies had tested the susceptibility of two macaque species, Macaca nemestrina and M. mulatta, to infection with the primate lymphotropic lentivirus SIVmne. In this report we describe the results obtained after infecting eleven M. fascicularis with SIVmne. Six of the animals had previously been immunized with a recombinant vaccinia virus expressing the envelope gene of HIV-1. All eleven animals became seropositive. To date ten animals have died 43 to 155 weeks post infection of an AIDS-like disease.
Databáze:	OpenAIRE
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