Abstract 14015: Right Ventricular Remodeling is Additive to Global Longitudinal Strain in Predicting Long Term Survival in Patients with Pulmonary Hypertension

Autor:	Akiko Goda, Keiko Ryo, Antonia M Delgado, Bhupendar Tayal, Marc Simon, Michael A Mathier, John Gorcsan
Rok vydání:	2014
Předmět:	Physiology (medical) Cardiology and Cardiovascular Medicine
Zdroj:	Circulation. 130
ISSN:	1524-4539 0009-7322
Popis:	Introduction: Right ventricular (RV) global longitudinal strain has been recently shown to be a marker of prognosis in patients with pulmonary hypertension (PH) but the additive role of RV remodeling on long term outcome is unclear. Hypothesis: Our aim was to test the hypothesis that RV remodeling measured by the RV area to left ventricular (LV) area ratio is additive to RV longitudinal strain in predicting prognosis in PH. Methods: We studied 120 PH patients, excluding patients with LVEF Results: The RV-LV area ratio was larger in PH patients than in normal control subjects as expected (0.64±0.09 vs. 1.18±0.59, p 0.73 was combined with RV global longitudinal strain > -15%, patients had a significantly worse prognosis compared to RV strain value or RV remodeling index alone (p=0.0017; Hazard Ratio 2.29, 95% confidence interval of 1.34 to 3.9). Conclusion: RV remodeling by the echocardiographic RV-LV area ratio was additive to RV global longitudinal strain at predicting long term outcomes in PH patients and has promise for clinical applications.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f4d78e0cdd34ab712023800aa210d498 https://doi.org/10.1161/circ.130.suppl_2.14015 Zobrazit plný text záznamu