Pedicled Vein Grafts in Coronary Surgery: Perioperative Data From a Randomized Trial

Autor: Anders Winnerkvist, Dag Nordhaug, Maryann Stenvik, Rune Wiseth, Knut Hegbom, Asbjørn Karevold, Per Magnus Haram, Øystein Pettersen, Alexander Wahba
Rok vydání: 2017
Předmět:
Zdroj: The Annals of Thoracic Surgery. 104:1313-1317
ISSN: 0003-4975
Popis: Background Less-than-optimal long-term patency of the saphenous vein is one of the main obstacles for the success of coronary artery bypass grafting (CABG). Results from the IMPROVE-CABG trial has shown that harvesting the saphenous vein with a pedicle of perivascular tissue less than 5 mm while using manual distention provides comparable occlusion rates but significantly less intimal hyperplasia at early follow-up. The impact of pedicled veins on duration of operations, leg wound infections, and postoperative bleeding is unknown. Methods One hundred patients undergoing first-time elective CABG were randomly assigned to conventional or pedicled vein harvesting. Perioperative and postoperative data were collected prospectively during the hospital stay and at follow-up. Results Duration of extracorporeal circulation was significantly longer in the pedicled vein group (mean: 76 min versus 65 min, p = 0.006); however, no significant difference was found in the cross-clamp time. No significant difference was found in intraoperative vein graft flow, postoperative bleeding, or leg wound infections (4% in each group). No reoperations were due to vein graft bleeding. Conclusions Harvesting a pedicled vein provides comparable postoperative bleeding and leg wound infection rates in selected patients. The technique is associated with a slightly longer duration of extracorporeal circulation than harvesting conventional veins. Promising early results using the pedicled vein technique may contribute to a change in standard vein harvesting technique for CABG in selected patients.
Databáze: OpenAIRE