Polyfluoroaromatic compounds with a NCClR group—a reactive type of polyfluoroarene

Autor:	T. D. Petrova, Vyacheslav E. Platonov
Rok vydání:	2005
Předmět:	Organic Chemistry Biochemistry Medicinal chemistry Multiple bonds Moderate temperature Inorganic Chemistry chemistry.chemical_compound chemistry Nucleophile Reagent Electrophile Environmental Chemistry Reactivity (chemistry) Physical and Theoretical Chemistry Nitrilium Heterocyclic derivatives
Zdroj:	Journal of Fluorine Chemistry. 126:860-876
ISSN:	0022-1139
DOI:	10.1016/j.jfluchem.2005.04.003
Popis:	This review deals with syntheses and reactivity of polyfluoroarenes with a N CClR group (including those with R Cl). The most promising and convenient methods of synthesis of these type compounds are based on co-pyrolysis reactions of low-basic polyfluoroaromatic amines with RCCl3 type derivatives and the interaction of such amines and polyfluoroaromatic hydrazines with RCX3 (X Cl,F) compounds in the presence of AlCl3 at moderate temperature; they have no analogues in the nonfluorinated series. Reactions with different nucleophilic reagents, the formation of electrophilic intermediates of the nitrilium cation type and reactions of the latter with aromatic and fluoroaromatic hydrocarbons, amines, and compounds with C N, C≡N and C O multiple bonds are described. It is shown that polyfluoroaromatic compounds with a N CClR group are promising precursors for syntheses of a wide range of compounds of various classes, including heterocyclic derivatives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f4d129dd7d7dd8240c1f079a5aa68983 https://doi.org/10.1016/j.jfluchem.2005.04.003 Zobrazit plný text záznamu Full Text from ScienceDirect