Macroprolactinémie, une variété d'hyperprolactinémie. À propos de cinq observation

Autor: V Recchi, G. Creisson, Canivet B, Freychet P, I Morange, S Hieronimus
Rok vydání: 1997
Předmět:
Zdroj: La Revue de Médecine Interne. 18:320-323
ISSN: 0248-8663
DOI: 10.1016/s0248-8663(97)84018-0
Popis: Macroprolactinemia, due to increased circulating levels of large molecular weight forms of prolactin, results in elevated level of immuno-reactive prolactin. The big variants have only weak biological activity; thus macroprolactinemia appears as a case of hyperprolactinemia without clinical significance as demonstrated by the five patients described. The diagnosis is based upon chromatography which separates the hormone and its variants. This disorder produces a pitfall in the diagnostic evaluation of hyperprolactinemia.
Databáze: OpenAIRE