Autor: |
V Recchi, G. Creisson, Canivet B, Freychet P, I Morange, S Hieronimus |
Rok vydání: |
1997 |
Předmět: |
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Zdroj: |
La Revue de Médecine Interne. 18:320-323 |
ISSN: |
0248-8663 |
DOI: |
10.1016/s0248-8663(97)84018-0 |
Popis: |
Macroprolactinemia, due to increased circulating levels of large molecular weight forms of prolactin, results in elevated level of immuno-reactive prolactin. The big variants have only weak biological activity; thus macroprolactinemia appears as a case of hyperprolactinemia without clinical significance as demonstrated by the five patients described. The diagnosis is based upon chromatography which separates the hormone and its variants. This disorder produces a pitfall in the diagnostic evaluation of hyperprolactinemia. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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