| Popis: |
1. 1. When two previously isolated male CF-1 mice are placed together, they will fight to establish a dominant-subordinate relationship. 2. 2. In response to this behaviorly stressful situation, various physiological and biochemical parameters in the mice are altered. 3. 3. When compared to dominants and controls, subordinates showed decreased hemoglobin concentration and bicarbonate levels, with a concomitant increase in hydrogen ion concentration, negative base excess and blood lactate levels. PCO 2 and PO 2 remained unchanged. 4. 4. No significant differences were observed in levels of 2,3-diphosphoglyceric acid in dominants, subordinates or controls. 5. 5. Subordinate individuals were anemic with persistent lactic acidemia reflecting the inability of the liver to catabolize excess lactate. |
