Evaluation of Analgetic Effect of Dexalginum 25 (Dexketoprofen) in Traumatology and Orthopaedics
| Autor: | Garkavi A, A A Sorokin, Ali Kader, Silin L L, Kavalerskiy G M, G M Kavalerskiy, A V Garkavi, L L Silin, Sorokin A A, Kader Ali |
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| Rok vydání: | 2004 |
| Předmět: |
Drug
medicine.medical_specialty Side effect Narcotic business.industry medicine.medical_treatment media_common.quotation_subject General Engineering Chronic pain Energy Engineering and Power Technology Opium Traumatology medicine.disease Dexketoprofen Anesthesia medicine Tramadol business medicine.drug media_common |
| Zdroj: | N.N. Priorov Journal of Traumatology and Orthopedics. 11:61-65 |
| ISSN: | 2658-6738 0869-8678 |
| DOI: | 10.17816/vto200411161-65 |
| Popis: | Clinical testing of analgetic effect and safety of nonsteroid anti-inflammatory drug dexalginum 25 was conducted in 45 patients with injuries and pathology of loco-motor system. Control group (49 patients with similar pathology and manifestation of pain syndrome) was treated by opium analgetic tramadol retard. It was shown that dexalgin 25 in therapeutic doses possessed analgetic effect in acute and chronic pains of various severity. The highest efficacy of the drug was noted in acute pains of medium and moderate severity. In patients with very severe pains dexalgin 25 allowed to decrease narcotic analgetics dose by 2 times. Dexalgimun 25 provided chronic pain relief only within the period of its use. Side effect were noted 2.7 times rarely in comparison to tramadol retard and such effect were less marked. Rate «favor-risk* of unsteroid anti-inflammatory drug dexalginum 25 was better than in opium analgetic tramadol retard. |
| Databáze: | OpenAIRE |
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