Heptalene Synthesis by Addition of Aryl Acetylenes to Azulenes

Autor:	Ksenia R. Briling, Dimitri N. Laikov
Rok vydání:	2020
Předmět:	chemistry.chemical_compound Reaction mechanism chemistry 010405 organic chemistry Aryl Yield (chemistry) Organic Chemistry Guaiazulene Heptalene Molecule 01 natural sciences Combinatorial chemistry 0104 chemical sciences
Zdroj:	Russian Journal of Organic Chemistry. 56:569-575
ISSN:	1608-3393 1070-4280
DOI:	10.1134/s1070428020040028
Popis:	Aryl acetylenes bearing electron-withdrawing groups have been found that can add to azulenes and yield 1,2-substituted heptalenes. Theoretical studies of the reaction mechanism helped to design the candidate molecules that have then been tested in the synthetic work. New heptalenes are obtained by reacting methyl (4-nitrophenyl)propiolate with either 4,6,8-trimethylazulene or guaiazulene, as well as 3-(4-nitrophenyl)-2-propyn-1-ol with guaiazulene. This opens a new synthetic route to 1-aryl-substituted heptalenes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f47c2dfc7abe35b23bc0924b60dd84eb https://doi.org/10.1134/s1070428020040028 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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