IMC29 Plays an Important Role in Toxoplasma Endodyogeny and Reveals New Components of the Daughter-Enriched IMC Proteome

Autor: Peter S. Back, Andy S. Moon, Rebecca R. Pasquarelli, Hannah N. Bell, Juan A. Torres, Allan L. Chen, Jihui Sha, Ajay A. Vashisht, James A. Wohlschlegel, Peter J. Bradley
Rok vydání: 2023
Předmět:
Zdroj: mBio. 14
ISSN: 2150-7511
DOI: 10.1128/mbio.03042-22
Popis: The inner membrane complex (IMC) is a conserved structure across the Apicomplexa phylum, which includes obligate intracellular parasites that cause toxoplasmosis, malaria, and cryptosporidiosis. The IMC is critical for the parasite to maintain its intracellular lifestyle, particularly in providing a scaffold for daughter bud formation during parasite replication.
Databáze: OpenAIRE