Systemic Lupus Erythematosus: Considerations in Diagnosis and Management for the Inpatient Dermatologist
| Autor: | David R. Pearson, Nikifor K. Konstantinov |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Acute cutaneous lupus erythematosus
medicine.medical_specialty Rowell syndrome Systemic lupus erythematosus Angioedema Cutaneous eruptions business.industry Hospitalized patients Dermatology Disease medicine.disease 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine immune system diseases 030220 oncology & carcinogenesis medicine Neonatal lupus erythematosus medicine.symptom skin and connective tissue diseases business |
| Zdroj: | Current Dermatology Reports. 9:220-230 |
| ISSN: | 2162-4933 |
| DOI: | 10.1007/s13671-020-00312-3 |
| Popis: | Hospitalization of systemic lupus erythematosus (SLE) patients is frequent and most often due to disease flares and infection. Herein, we describe the clinical features and therapy for specific and nonspecific cutaneous manifestations of hospitalized lupus patients. New insights of the pathogenic mechanisms of SLE allow consideration of novel therapeutic targets and strategies. The precise role of these treatments for hospitalized SLE patients requires further study. Severe lupus-specific cutaneous eruptions important for the inpatient dermatologist include acute cutaneous lupus erythematosus (ACLE), toxic-epidermal necrosis (TEN)-like ACLE, Rowell syndrome (RS), and bullous systemic lupus erythematosus (BSLE). Neonatal lupus erythematosus (NLE) and several chronic cutaneous lupus eruptions are also important considerations. Vascular manifestations and angioedema are non-specific cutaneous presentations that may cause significant morbidity and mortality. Careful assessment by a dermatologist will assist in the diagnosis and management of hospitalized patients with SLE. |
| Databáze: | OpenAIRE |
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